Showing posts with label recommendations. Show all posts
Showing posts with label recommendations. Show all posts

Wednesday, October 15, 2014

What's in my microbiome?

Although I was an early customer of 23andme, I found the results unsatisfying because there is so little that is actionable. I mean, you don't need a test to tell you that you have green eyes or that you're lactose intolerant. And if you have some weird disease in your future, the main advice -- eat well, get exercise, buy life insurance -- applies to everyone whether you know you're at risk or not. Although I think it's fun and interesting for its own sake, I frankly understand why normal people wouldn't bother.

That's why I'm now so intrigued with the microbiome, that collection of hundreds of species of bacteria and other microbes that live all over you, inside and out. In total, they weigh about as much as your brain; it's as if your body has a whole other organ that you can't see. Massive improvements in genetic sequencing technology over the past decade have suddenly brought the ability to view and measure this micro-world, and important new discoveries are happening every day.

The best part? you can change your microbes! It can be difficult, because once these things have found a foothold somewhere in your body, they don't want to let go, but at least it's possible, whether through eating different foods or supplements (fermented products, probiotics, fiber) or by avoiding antibiotics (including germ-killing hand sanitizers), your actions have an affect your microbiome. So if you don't like something, you can (at least in theory) change it.

To find out what's in my microbiome now, I bought a $400 kit from the San Francisco company uBiome. For that, I received swabs for my mouth, gut, genitals, nose, and skin. The most interesting one is the gut, which you can buy for $89, and is the one I'd most recommend. After you collect the samples (warning for the squeamish: it involves soiled toilet paper), send them back and they give you results like this:

The microbiome is so complicated -- we're dealing with hundreds of different species, each with its own genome -- that it's hard to summarize in a single, quick takeaway. The web site lets you dive deeper into the various strains of bacteria, looking at the results organized by phylum/class/order/family/genus, digging into more detail at each level. Since each user fills out a detailed questionnaire when returning the sample, you can compare your results to self-described vegans, paleo dieters, and several other categories to see how you stack up to people who have been gaining or losing weight recently, for example.

The tools on the site are fantastic, and they are obviously putting more effort into improving them (they've become noticeably better just in the past few weeks). Better yet, you can download all of your results in XML format to keep forever, or analyze anyway you like.

My only complaint was the amount of time it took to get results: a full three months for this sample. Their customer support staff is very responsive -- I always got a helpful response within a few hours, even on weekends -- but I do wish it didn't take so long.

But frankly that complaint rings hollow when I consider how long it will take me to understand the plethora of fascinating torrent of data I got back. You can see from the chart above that I have more of certain types of bacteria than their average customer. Is that good? bad? neutral? Who knows?

This is not uBiome's fault. Science just hasn't figured out these answers yet. In my case, I'm a healthy, fit, normal-weight omnivore, so I assume that the percentage differences with "Average" are perfectly fine, but I could imagine how somebody with weight or other problems might be concerned if they saw something significantly different from average. The good news is that, in theory, you can change your results, but the bad news is that science really has little clue exactly how to do that, or even what constitutes "good".

Because the technology is so new, you may find that your snapshot looks different each time you take the test. Sometimes people report different results from different locations on the same sample. So it's best not to read much into of any findings yet. Still, it's the ability to change your microbiome that makes all the difference and I expect to learn much more as the science progresses.


Sunday, May 25, 2014

Who has the most accurate health news?


The independent site Health News Review evaluated nearly 2000 health-related news articles since 2006, ranking their accuracy and usefulness according to these criteria: cost, benefits, harm, veracity, exaggeration, availability, and the source and conflicts of interest of the promoters:

Here are the rankings:

Associated Press 3.61
NPR 3.57
Los Angeles Times 3.51
New York Times 3.49
Wall Street Journal 3.4
Reuters Health 3.24
CNN Health 2.98
US News 2.97
HealthDay 2.9
Time 2.81
WebMD 2.77
MSNBC 2.38

I was surprised that AP did so well, and WebMD so poorly.


Tuesday, May 26, 2009

Sharpen your lawnmower blade

You’re supposed to do it once a season, but Consumer Reports says that 25% of owners never sharpen their lawnmower blades. I’m happy to report that I no longer fit in that lazy category, and found to my delight that it was easier than I thought.

First step was to pin the blade down in such a way that it wouldn’t harm me while taking it off the mower.  The directions say use a 2x4 board, but I didn’t have one handy, and I found that a brick works just fine.  In my case, a quick counter-clockwise turn of the main bolt was enough to remove the blade safely.

Sharpening a lawnmower blade.

 

How to sharpen the blade: I suppose I could have found my own sharpener (I hear you can buy a small $4 blade sharepner that works with any power drill for example) but that was too much hassle.  People say that local plant nurseries, or hardware stores will sharpen the blade (for free?) but after some calls to Lowes and Home Depot, I came up with nothing.  Eventually I discovered that our local equipment rental place (Eastside Rental, in Bellevue) would do it while I wait.  They charged an exorbitant $11, but it was worth it.

You should see how much better my lawn looks now!

Monday, November 10, 2008

Purple toes in Zillah

There are no wine lovers in the San Francisco Bay Area (or in Seattle for that matter) who haven’t been to Napa Valley.  But comparatively few people know about a  similar wine-growing region just two hours east of Mercer Island (over the soon-to-be-tolled I-90 bridge), in the Rattlesnake Hills area of the Yakima Valley.  We spent our weekend there, where some good friends are getting started with their own winery.

First, we picked some grapes:

IMG_7209

then we crushed them:

Stomping grapes

and now look at the toes on my 6-year-old:

Stomping grapes

You should go too!  Best place to stay in Zillah is the Comfort Inn, for about $100/night, including a big breakfast, a pool, and free use of their grill!

Sunday, September 28, 2008

Konga at Trabant Coffee

Mike at Trabant Coffee and Chai saw that I was looking for more Ethiopia Yergcheffe Konga coffee (it’s sooo good!), and let me know that a new batch is now available from 49th Parallel Roasters and it’s in stock now in Seattle.  So I rushed over to their Pioneer Square store and picked up a fresh 12-oz bag and this morning I enjoyed another, heavenly-wonderful, handmade raw milk latte with those excellent beans.

49th parallel konga coffee

I even gave a cup to the piano teacher at our house this afternoon.  She’ll be back, I assure you.

Sunday, May 18, 2008

Seattle Cheese Festival

We love cheese as much as we like good tofu, so of course we also dropped in on the Seattle Cheese Festival, held this weekend at Pike Place Market.  The best part of course is the sampling (suggested donation $5), though the crowds are disorganized and the lines are long, so you really have to want your samples.

Here are the ones we liked best:

  • Marin French Cheese Company (try their malange brie)
  • Sierra Nevada Cheese Company (excellent traditional and garlic cream cheese, available at PCC)
  • Sartori Reserve (SarVecchio parmesan is best)

 

seattle cheese festival

Thursday, February 14, 2008

Speak up about Softcare Dental Bellevue

A friend, somebody I trust, says she was intimidated by a dentist, Softcare Dental, in Bellevue Washington. It's making her think twice now about posting reviews on the Internet.

I say no way! Speak up! If you had a bad experience, say so. If you had a good experience, say so.

I know nothing at all about this dentist, other than my friend's opinion and what I just read on the internet. I may be wrong.  But I note that (most?) of the "good" reviews are suspicious.  Posted the same day, by anonymous people who didn't post any other reviews.  I don't believe them.  I believe my friend.

If  this dentist wants to intimidate me for posting my concerns, she's welcome to email me or call me.  Meanwhile, there are just too many good dentists out there (like Dr. Nadeem Merchant, who I use) so why bother risking your teeth with Softcare Dental?

By the way, I disagree with my friend on one thing:  I prefer to post under my real name. <insert counter-arguments here>  I know, I know, but the psychos will find you anyway and when they do, your transparency will be an asset.